笔贰尝滨3蛋白抗体
规格：1尘驳/1尘濒
英文名： PELI3
别名： E3 ubiquitin protein ligase pellino homolog 3; MGC35521; PEL 13; Peli3; PELI3_HUMAN; Pellino 3; Pellino 3 alpha; Pellino E3 ubiquitin protein ligase family member 3; Pellino homolog 3 (Drosophila); Pe
分子量： 48kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PELI3
交叉反应：Human, Mouse, Rat, Rabbit, Guinea Pig,
细胞定位：
笔贰尝滨3蛋白抗体产物介绍：background: The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011] Function: Scaffold protein which probably links Toll-like receptors (TLRs) to basic cellular processes via its interaction with the complex containing 笔贰尝滨3蛋白抗体IRAK kinases and TRAF6. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. Probably involved in innate immune response. Tissue Specificity: Highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach. Isoform 1 is not expressed in lung. Similarity: Belongs to the pellino family. Database links: Entrez Gene: 246330 Human笔贰尝滨3蛋白抗体 Entrez Gene: 240518 Mouse Entrez Gene: 309157 Rat Omim: 609827 Human SwissProt: Q8N2H9 Human SwissProt: Q8BXR6 Mouse Unigene: 656875 Human Unigene: 277580 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
笔贰尝滨3蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid