磷酸化血小板源性生长因子受体α抗体
规格：1尘驳/1尘濒
英文名： phospho-PDGFRA (Tyr720)
别名： PDGF Receptor alpha (phospho Y720); p-PDGF Receptor alpha (phospho Y720); Alpha-type platelet-derived growth factor receptor; CD140 antigen-like family member A; CD140a; CD140a antigen; MGC74795; PDGF
分子量： 199kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
磷酸化血小板源性生长因子受体α抗体产物介绍：background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stroma磷酸化血小板源性生长因子受体α抗体 tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012] Function: Receptor that binds both PDGFA and PDGFB and has a tyrosine-protein kinase activity. Subcellular Location: Membrane. Tissue Specificity: Expressed in primary and metastatic colon tumors and in normal colon tissue. Tumors may express a different isoform to that found in normal tissue. DISEASE: Note=A chromosomal aberration involving PDGFRA is found in some cases of hypereosinophilic syndrome. Interstitial chromosomal deletion del(4)(q12q12) causes the fusion 磷酸化血小板源性生长因子受体α抗体of FIP1L1 and PDGFRA (FIP1L1-PDGFRA). Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. Contains 5 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 protein kinase domain. Gene ID: 5156 Database links: Entrez Gene: 5156 Human Entrez Gene: 18595 Mouse Entrez Gene: 25267 Rat Omim: 173490 Human SwissProt: P16234 Human SwissProt: P26618 Mouse SwissProt: P20786 Rat Unigene: 74615 Human Unigene: 221403 Mouse Unigene: 55127 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化血小板源性生长因子受体α抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 生长因子和** 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid