细胞间粘附分子-2抗体
规格:1尘驳/1尘濒
英文名: ICAM-2/CD102
别名: CD102; Intercellular adhesion molecule 2; CD102 antigen; ICAM 2; ICAM-2; ICAM2; Intercellular adhesion molecule 2 precursor; Ly60.
分子量: 28kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ICAM-2
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
细胞间粘附分子-2抗体产物介绍:background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by 细胞间粘附分子-2抗体RefSeq, Jul 2008] Function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.细胞间粘附分子-2抗体 Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in endothelial cells and leukocytes. High levels found in lung. Similarity: Belongs to the immunoglobulin superfamily. ICAM family. Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Gene ID: 3384 Database links: Entrez Gene: 3384 Human Entrez Gene: 15896 Mouse Omim: 146630 Human SwissProt: P13598 Human SwissProt: P35330 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ICAM-2也是**蛋白超家族粘附分子之一.
细胞间粘附分子-2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞粘附分子 细胞表面分子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid