磷酸二酯酶6δ抗体
规格：1尘驳/1尘濒
英文名： PDE6D
别名： PDE6 delta; 5''-cyclic phosphodiesterase subunit delta; GMP PDE delta; GMP-PDE delta; p17 protein; PDE 6; PDE 6D; PDE D; PDE6; PDE6D; PDE6D_HUMAN; PDED; Phosphodiesterase 6D cGMP specific; Phosphodies
分子量： 17kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDE6D
交叉反应：Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Zebrafish,
细胞定位：细胞膜
磷酸二酯酶6δ抗体产物介绍：background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014] Function: Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does 磷酸二酯酶6δ抗体so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation. Tissue Specificity: Retina. Similarity: Belongs to the PDE6D/unc-119 family. Gene ID: 5147 Database links: Entrez Gene: 281976 Cow Entrez Gene: 403781 Dog Entrez Gene: 5147 Human Entrez Gene: 18582 Mouse Entrez Gene: 363272 Rat Omim: 602676 Human SwissProt: Q95142 Cow SwissProt: 磷酸二酯酶6δ抗体Q9XT54 Dog SwissProt: O43924 Human SwissProt: O55057 Mouse Unigene: 516808 Human Unigene: 12925 Mouse Unigene: 44816 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸二酯酶6δ抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid