纤维母细胞生长因子4抗体
规格：1尘驳/1尘濒
英文名： FGF4
别名： Fibroblast Growth Factor4; Heparin Secretory Transforming Protein 1; Kaposi Sarcoma Oncogene; Fgf-4; Fgfk; Hstf-1; kFGF; KS3;MGC129266; MGC129267; HBGF-4; HST; HST-1; HSTF1; K-FGF; KS3; FGF4_HUMAN.
分子量： 19kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FGF4
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
纤维母细胞生长因子4抗体产物介绍：background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was纤维母细胞生长因子4抗体 found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq]. Function: Can transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity. Subunit: Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.纤维母细胞生长因子4抗体 Subcellular Location: Secreted. Similarity: Belongs to the heparin-binding growth factors family. Gene ID: 2249 Database links: Entrez Gene: 2249 Human Entrez Gene: 14175 Mouse Entrez Gene: 116499 Rat Omim: 164980 Human SwissProt: P08620 Human SwissProt: P11403 Mouse Unigene: 1755 Human Unigene: 4956 Mouse Unigene: 81223 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 转录调节因子（Transcriptin Regulators） 纤维母细胞生长因子4是FGF家族的chengyu7成员。FGF家族参与一系列的生理功能：胚胎发育、细胞生长、器官形成、组织修复、肿瘤生长和侵袭。FGF3/FGF4在很多恶性肿瘤中呈高表达，被认为原癌基因之一。
纤维母细胞生长因子4抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 生长因子和** 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid