肌动蛋白相关蛋白2/3亚型4抗体
规格：1尘驳/1尘濒
英文名： ARPC4
别名： Actin related protein 2/3 complex subunit 4; Actin related protein 2/3 complex subunit 4 20 kD; Actin related protein 2/3 complex subunit 4 20kDa; Actin-related protein 2/3 complex subunit 4; ARC20; A
分子量： 20kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ARPC4/p2
交叉反应：Human, Mouse, Rat, Chicken, Cow, Rabbit, Zebrafish, Sheep, Xenopus laevis
细胞定位：细胞浆
肌动蛋白相关蛋白2/3亚型4抗体产物介绍：background: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 肌动蛋白相关蛋白2/3亚型4抗体(TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]. Function: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Subunit: Component of the肌动蛋白相关蛋白2/3亚型4抗体Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC. Subcellular Location: Cytoplasm; cytoskeleton. Cell projection. Similarity: Belongs to the ARPC4 family. Database links: Entrez Gene: 10093 Human Entrez Gene: 68089 Mouse Entrez Gene: 539459 Cow Entrez Gene: 100155875 Pig Entrez Gene: 297518 Rat Entrez Gene: 114456 Zebrafish Omim: 604226 Human SwissProt: Q148J6 Cow SwissProt: P59998 Human SwissProt: P59999 Mouse Unigene: 323342 Human Unigene: 289306 Mouse Unigene: 472172 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌动蛋白相关蛋白2/3亚型4抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 结合蛋白 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid