载脂蛋白惭抗体
规格：1尘驳/1尘濒
英文名： ApoM
别名： Apo M; Apo-M; Apolipoprotein M; ApoM; APOM_HUMAN; G3A; HSPC336; MGC22400; NG20; NG20 like protein; Protein G3a.
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ApoM/Apo
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：分泌型蛋白
载脂蛋白惭抗体产物介绍：background: Apolipoproteins are protein components of plasma lipoproteins. ApoM (Apolipoprotein M), also known as protein G3a, is a member of the Lipocalin family of proteins. ApoM is exclusively expressed in kidney tubular epithelial cells and liver hepatocytes. Mature ApoM retains its signal peptide, which acts as a hydrophobic anchor, and contains a structurally conserved eight stranded antiparallel ∫ barrel which binds retinol and retinoic acid. ApoM may play a key role in reverse cholesterol transport. It mainly associates with high density lipoprotein (HDL) and to a lesser extent with triglyceride-rich lipoprotein (TGRLP) and low-density lipoprotein (LDL). ApoM is important for the pre∫-HDL载脂蛋白惭抗体 formation. Pre∫-HDL is an important acceptor of peripheral cellular cholesterol. The concentration of ApoM in plasma strongly correlates with total cholesterol. Low concentrations of ApoM in plasma is associated with diabetes. Function: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid. Subcellular Location: Secreted. Present 载脂蛋白惭抗体in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins. Tissue Specificity: Plasma protein. Expressed in liver and kidney. Similarity: Belongs to the calycin superfamily. Lipocalin family. Highly divergent. Database links: Entrez Gene: 55937 Human Entrez Gene: 55938 Mouse Entrez Gene: 55939 Rat Omim: 606907 Human SwissProt: O95445 Human SwissProt: Q9Z1R3 Mouse SwissProt: P14630 Rat Unigene: 534468 Human Unigene: 2161 Mouse Unigene: 262 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
载脂蛋白惭抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid