自噬相关蛋白8础抗体
规格：1尘驳/1尘濒
英文名： APG8A
别名： APG8A (autophagy 8A); AT4G21980; ATG8; ATG8A; Autophagy 8A; Autophagy related protein 8a; Autophagy related ubiquitin like modifier ATG8a; F1N20.80; F1N20_80; ATG8A_ARATH.
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Arabidopsis th
交叉反应：Arabidopsis thaliana
细胞定位：细胞浆 细胞膜
自噬相关蛋白8础抗体产物介绍：background: APG8A is involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. It may mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Function: Involved in cytoplasm to vacuole transport (Cvt) vesicles and autophagosomes formation. May mediate the delivery of the vesicles and autophagosomes to the vacuole via the microtubule cytoskeleton. Subunit: Interacts with ATG4b. Subcellular Location: Cytoplasmic vesicle ?cvt 自噬相关蛋白8础抗体vesicle membrane; Lipid-anchor. Cytoplasmic vesicle ?autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor. Note= Membrane-associated through a lipid anchor. Post-translational modifications: The C-terminal 5 residues are removed by ATG4自噬相关蛋白8础抗体to expose Gly-117 at the C-terminus. This Gly-117 forms then a thioester bond with the 'Cys-558' of ATG7 (E1-like activating enzyme) before being transferred to the 'Cys-258' of ATG3 (the specific E2 conjugating enzyme), in order to be finally amidated with phosphatidylethanolamine. This lipid modification anchors ATG8 to autophagosomes (By similarity). Similarity: Belongs to the MAP1 LC3 family. Database links: UniProtKB/Swiss-Prot: Q8LEM4.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
自噬相关蛋白8础抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白 表观遗传学 泛素
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid