锚定蛋白重复结构域蛋白激酶础狈碍碍1抗体
规格：1尘驳/1尘濒
英文名： ANKK1
别名： Ankyrin repeat and kinase domain containing 1; Ankyrin repeat and protein kinase domain containing protein 1; EC 2.7.11.1; PKK2; Protein kinase PKK2; SGK288; Sugen kinase 288; X kinase; ANKK1_HUMAN.
分子量： 85kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ANKK1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Horse,
细胞定位：
锚定蛋白重复结构域蛋白激酶础狈碍碍1抗体产物介绍：background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein锚定蛋白重复结构域蛋白激酶础狈碍碍1抗体 kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Function: ANKK1 belongs to the TKL Ser/Thr protein kinase superfamily, contains 锚定蛋白重复结构域蛋白激酶础狈碍碍1抗体twelve ANK repeats and one protein kinase domain. The protein is weakly expressed in testis, placenta, and spinal cord. Tissue Specificity: Highly expressed in brain and weakly expressed in placenta and spinal cord. Similarity: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Contains 12 ANK repeats. Contains 1 protein kinase domain. Database links: UniProtKB/Swiss-Prot: Q8NFD2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锚定蛋白重复结构域蛋白激酶础狈碍碍1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 细胞凋亡 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid