γ-氨基丁酸醛脱氢酶抗体
规格:1尘驳/1尘濒
英文名: ALDH9A1
别名: 4 trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Ald
分子量: 54kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ALDH9A1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆
γ-氨基丁酸醛脱氢酶抗体产物介绍:background: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation ofγ-氨基丁酸醛脱氢酶抗体 a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction. Function: Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Subunit: Homotetramer. Subcellular Location: Cytoplasm. Tissue Specificity: High expression in liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas,γ-氨基丁酸醛脱氢酶抗体 with the highest levels in the spinal cord and the lowest in the occipital pole. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the aldehyde dehydrogenase family. Gene ID: 233 Database links: Entrez Gene: 223 Human Entrez Gene: 56752 Mouse Entrez Gene: 64040 Rat Omim: 602733 Human SwissProt: P49189 Human SwissProt: Q9JLJ2 Mouse SwissProt: Q9JLJ3 Rat Unigene: 2533 Human Unigene: 330055 Mouse Unigene: 474999 Mouse Unigene: 98155 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ-氨基丁酸醛脱氢酶抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid