肌动蛋白调节蛋白颁础笔骋抗体
规格：1尘驳/1尘濒
英文名： Actin Regulatory Protein CAPG
别名： Actin capping protein GCAP39; Actin regulatory protein CAP G; Actin regulatory protein CAP-G; AFCP; CAPG; CAPG_HUMAN; Capping protein (actin filament) gelsolin like; Capping protein gelsolin like; gCa
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Actin Re
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞核 细胞浆
肌动蛋白调节蛋白颁础笔骋抗体产物介绍：background: Caldesmon, Filamin 1, Nebulin, Plastin, ADF, Gelsolin, CapG, Dematin and Cofilin are differentially expressed Actin-binding proteins. Both muscular (CDh) and non-muscular (CD1) forms of Caldesmon bind to Actin as well as to Calmodulin and Myosin. CDh is expressed predominantly on thin filaments in smooth muscle, whereas CD1 is widely expressed in non-muscle tissues and cells. CapG, also designated Actin-regulatory protein and macrophage-capping protein, is a macrophage-specific protein that reversibly blocks the barbed ends of Actin filaments, but does not sever preformed ones. The interactions of CapG with Actin may be important in the 肌动蛋白调节蛋白颁础笔骋抗体regulation of nuclear and cytoplasmic structures. CapG is a calcium-sensitive DNA-binding protein that plays a role in macrophage function. It is expressed in macrophages and macrophage-like cells and can localize both to the nucleus and the cytoplasm. Function: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. Subcellular Location: Cytoplasm. Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.肌动蛋白调节蛋白颁础笔骋抗体 Tissue Specificity: Macrophages and macrophage-like cells. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the villin/gelsolin family. Contains 3 gelsolin-like repeats. Gene ID: 822 Database links: Entrez Gene: 353121 Cow Entrez Gene: 822 Human Entrez Gene: 12332 Mouse Entrez Gene: 297339 Rat Omim: 153615 Human SwissProt: Q865V6 Cow SwissProt: P40121 Human SwissProt: P24452 Mouse SwissProt: Q6AYC4 Rat Unigene: 516155 Human Unigene: 18626 Mouse Unigene: 8945 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌动蛋白调节蛋白颁础笔骋抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid