狂躁基因同源蛋白惭贵狈骋抗体
规格：1尘驳/1尘濒
英文名： Manic Fringe
别名： 3-N-acetylglucosaminyltransferase manic fringe; Beta-1; Beta-1,3-N-acetylglucosaminyltransferase manic fringe; MFNG; MFNG_HUMAN; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Manic Fr
交叉反应：Human, Mouse, Rat, Cow, Horse, Sheep, Chimpanzee,
细胞定位：细胞浆 细胞膜
狂躁基因同源蛋白惭贵狈骋抗体产物介绍：background: Three mammalian fringe family members, Manic, Radical and Lunatic Fringe, have been identified as proteins related to Drosophila fringe, a protein involved in development. Fringe proteins act upstream of the Notch signaling pathway and are involved in boundary determination during segmentation. Each mammalian fringe displays different patterns of expression, though all are expressed in the mouse embryo as well as in many tissues. Radical fringe plays a key role in the development of the limb bud.狂躁基因同源蛋白惭贵狈骋抗体 Lunatic fringe is required for normal somite segmentation and patterning and is thought to be a target of the molecular clock. Manic fringe, also involved in somatic development, has been shown to render mouse NIH/3T3 cells tumorigenic in SCID mice. Function: Glycosyltransferase involved in the elongation of O-linked ligands to activate Notch signaling. Possesses fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity. Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the glycosyltransferase 31 family. Database links: Entrez Gene:狂躁基因同源蛋白惭贵狈骋抗体 4242 Human Entrez Gene: 17305 Mouse Entrez Gene: 315119 Rat Omim: 602577 Human SwissProt: O00587 Human SwissProt: O09008 Mouse Unigene: 517603 Human Unigene: 149235 Mouse Unigene: 102109 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
狂躁基因同源蛋白惭贵狈骋抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid