丝裂原诱导蛋白2抗体
规格：1尘驳/1尘濒
英文名： Kindlin 2
别名： FLJ34213; FLJ44462; UNC112; FERM2_HUMAN; Fermitin family homolog 2; Fermt2; KIND2; Kindlin-2; MIG-2; MIG2; Mitogen-inducible gene 2 protein; PH domain-containing family C member 1; Pleckstrin homology
分子量： 78kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Kindlin
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆 细胞膜
丝裂原诱导蛋白2抗体产物介绍：background: Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumor tissues. Function: Participates in the connection between ECM adhesion sites and the actin cytoskeleton and also in the丝裂原诱导蛋白2抗体orchestration of actin assembly and cell shape modulation. Recruits migfilin (FBLP1) protein to cell-ECM focal adhesion sites. Subunit: Interacts with FBLP1. Subcellular Location: Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Note=Within actin stress fibers at cell-ECM focal adhesion sites. Tissue Specificity: Ubiquitous. Found in numerous tumor tissues. Similarity: Belongs to the kindlin 丝裂原诱导蛋白2抗体family. Contains 1 FERM domain. Contains 1 PH domain. Database links: Entrez Gene: 10979 Human Entrez Gene: 218952 Mouse Entrez Gene: 289992 Rat Entrez Gene: 616981 Cow Omim: 607746 Human SwissProt: Q96AC1 Human SwissProt: Q8CIB5 Mouse Unigene: 509343 Human Unigene: 210018 Mouse Unigene: 7658 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝裂原诱导蛋白2抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 发育生物学 信号转导 干细胞 细胞粘附分子 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid