囊包蛋白/内披蛋白抗体
规格：1尘驳/1尘濒
英文名： Involucrin
别名： INVO_HUMAN; involucrin; ivl.
分子量： 64kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Involucr
交叉反应：贬耻尘补苍,
囊包蛋白/内披蛋白抗体细胞定位：细胞浆
产物介绍：background: Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008]. Function: Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. Subunit: Directly or indirectly cross-linked to cornifelin (CNFN). Subcellular Location: Cytoplasm. Tissue Specificity: Keratinocytes of epidermis 囊包蛋白/内披蛋白抗体and other stratified squamous epithelia. Post-translational modifications: Substrate of transglutaminase. Some glutamines and lysines are cross-linked to other involucrin molecules, to other proteins such as keratin, desmoplakin, periplakin and envoplakin, and to lipids like omega-hydroxyceramide. Similarity: Belongs to the involucrin family. Gene ID: 3713 Database links: Entrez Gene: 3713 Human Entrez Gene: 16447囊包蛋白/内披蛋白抗体 Mouse Entrez Gene: 60583 Rat Omim: 147360 Human SwissProt: P07476 Human SwissProt: P48997 Mouse SwissProt: P48998 Rat Unigene: 516439 Human Unigene: 207365 Mouse Unigene: 142591 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 套膜蛋白又称内披蛋白或囊包蛋白，与毛透明蛋白共同构成角质细胞包膜支架的蛋白质。在角质细胞分化时，首先出现在表皮棘层的上层细胞中的标志性蛋白质，该蛋白在角质细胞和其他复层扁平上皮合成的蛋白。*初存在于细胞质中，然后通过转谷氨酰胺酶的作用，转变为交联的膜蛋白。
囊包蛋白/内披蛋白抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 细胞骨架 细胞外基质
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid