础厂颁尝2蛋白抗体
规格：1尘驳/1尘濒
英文名： ASCL2
别名： Achaete scute complex like 2; Achaete scute homolog 2; achaete-scute complex-like 2; Achaete-scute homolog 2; ASCL2; ASCL2_HUMAN; ASH-2; Ash2; bHLHa45; Class A basic helix-loop-helix protein 45; HASH2
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human ASCL2
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
细胞定位：细胞核
础厂颁尝2蛋白抗体产物介绍：background: Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiatio础厂颁尝2蛋白抗体. ASCL2 is a 193 amino acid protein that localizes to the nucleus and contains one bHLH domain. Expressed in developing placental tissue, ASCL2 binds to DNA and functions as a transcriptional regulator that is involved in the maturation of neuronal precursors in the peripheral and central nervous systems. Function: AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Subcellular Location: Nucleus. Tissue础厂颁尝2蛋白抗体 Specificity: Expressed specifically in the extravillous trophoblasts of the developing placenta. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Gene ID: 430 Database links: Entrez Gene: 430 Human Entrez Gene: 17173 Mouse Entrez Gene: 24209 Rat SwissProt: Q99929 Human SwissProt: O35885 Mouse SwissProt: P19360 Rat Unigene: 152475 Human Unigene: 196417 Mouse Unigene: 10486 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
础厂颁尝2蛋白抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导 干细胞 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid