滋养层细胞糖蛋白5罢4抗体
规格:1尘驳/1尘濒
英文名: 5T4
别名: 5T4; 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4AG; M6P1; TPBG; TPBG_HUMAN; Trophoblast glycoprotein.
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TPBG/5T4
交叉反应:Human, Mouse, Rat, Dog, Cow,
细胞定位:细胞膜
滋养层细胞糖蛋白5罢4抗体产物介绍:background: TPBG is a 420 amino acid single-pass type I membrane protein expressed by all types of trophoblasts as early as 9 weeks of development. TPBG contains an N-terminal putative signal sequence, a 310-residue extracellular region, a membrane anchorage domain and a 44-amino acid cytoplasmic tail with a potential phosphorylation site. The extracellular region has seven potential N-glycosylation sites and seven leucine-rich repeats, which are located in two regions separated by a hydrophilic stretch. 滋养层细胞糖蛋白5罢4抗体Suggested to be involved in cell adhesion, TPBG may also be associated with tumor growth and progression. Subcellular Location: Membrane. Tissue Specificity: Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma. 滋养层细胞糖蛋白5罢4抗体Similarity: Contains 6 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Gene ID: 7162 Database links: Entrez Gene: 7162 Human Entrez Gene: 21983 Mouse Entrez Gene: 83684 Rat Omim: 190920 Human SwissProt: Q13641 Human SwissProt: Q9Z0L0 Mouse SwissProt: Q5PQV5 Rat Unigene: 82128 Human Unigene: 20864 Mouse Unigene: 484180 Mouse Unigene: 43122 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
滋养层细胞糖蛋白5罢4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 发育生物学 干细胞 转录调节因子 糖蛋白 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid