肥大细胞羧肽酶础3抗体
规格:1尘驳/1尘濒
英文名: CPA3
别名: carboxypeptidase A; Carboxypeptidase A3; carboxypeptidase A3 mast cell; CBPA3_HUMAN; Cpa3; Mast cell carboxypeptidase A; mast cell carboxypeptidase A3; MC CPA; MC-CPA.
分子量: 36kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Human CPA3/MC-
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆
肥大细胞羧肽酶础3抗体产物介绍:background: Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localized to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic肥大细胞羧肽酶础3抗体 carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.肥大细胞羧肽酶础3抗体 Subcellular Location: Cytoplasmic vesicle, secretory vesicle. Secretory granules. Similarity: Belongs to the peptidase M14 family. Database links: Entrez Gene: 1359 Human Omim: 114851 Human SwissProt: P15088 Human Unigene: 646 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肥大细胞羧肽酶础3抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 信号转导 干细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid