骋颁狈罢1葡萄糖转移酶抗体
规格:1尘驳/1尘濒
英文名: GCNT1
别名: 3-galactosyl-O-glycosyl-glycoprotein beta-1; 6-N-acetylglucosaminyltransferase; Beta-1; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase; C2GNT; C2GNT L; C2GNT1; C2
分子量: 50kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Human GCNT1
交叉反应:Human, Mouse, Rat, Dog, Cow, Sheep,
细胞定位:细胞浆 细胞膜
骋颁狈罢1葡萄糖转移酶抗体产物介绍:background: GCNT1 is expressed in a variety of cell types, including lymphocytes and mucin-producing cells. Specifically, GCNT1 expression in leukocytes regulates the synthesis of core 2 O-glycans that carry sialyl-Lewis x (sLex) oligosaccharides, which confer high affinity binding to Selectins. Downregulation of Selectin ligand expression levels has been shown to inhibit 骋颁狈罢1葡萄糖转移酶抗体tissue infiltration. Therefore, GCNT1 represents a potential drug target for the treatment of inflammatory disorders and other pathologies involving Selectins. Function: Forms critical branches in O-glycans. Subcellular Location: Golgi apparatus membrane.骋颁狈罢1葡萄糖转移酶抗体 Tissue Specificity: Highly expressed in activated T-lymphocytes and myeloid cells. Similarity: Belongs to the glycosyltransferase 14 family. Database links: UniProtKB/Swiss-Prot: Q02742.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋颁狈罢1葡萄糖转移酶抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 糖蛋白 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid