内皮分泌蛋白厂颁鲍叠贰2抗体
规格:1尘驳/1尘濒
英文名: SCUBE2
别名: 4932442O19Rik; Cegb1; Cegf1; CEGP1; Cegp1 protein; CUB domain and EGF-like repeat containing 1; FLJ16792; FLJ35234; ICRFP703B1614Q5.1; MGC133057; Protein CEGP1; RGD1563998; SCUB2_HUMAN; Scube2; Signal
分子量: 107kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Human SCUBE2
交叉反应:Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
细胞定位:分泌型蛋白
内皮分泌蛋白厂颁鲍叠贰2抗体产物介绍:background: SCUBE2 is a 999 amino acid protein that is ubiquitously expressed in tissues and belongs to the evolutionarily conserved SCUBE protein family. Containing a CUB domain and nine EGF-like domains, SCUBE2 manifests as a secreted surface-anchored glycoprotein when overexpressed and is considered a novel component of the HH (Hedgehog) signal.内皮分泌蛋白厂颁鲍叠贰2抗体 The HH signal plays a pivotal role in induction of ventral neuronal and muscle cell types around the midline during vertebrate development. It is suggested that SCUBE2 expression is important in breast cancer progression and may serve as a useful prognostic marker. SCUBE2 forms homo-oligomers and hetero-oligomers with SCUBE1 and SCUBE3. Expressed as three isoforms produced by alternative splicing events, SCUBE2 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the内皮分泌蛋白厂颁鲍叠贰2抗体 human genome. Subunit: Forms homooligomers and heterooligomers with SCUBE1 and SCUBE3 (By similarity). Subcellular Location: Secreted. Tissue Specificity: Expressed in a broad spectrum of tissues. Similarity: Contains 1 CUB domain. Contains 9 EGF-like domains. Database links: UniProtKB/Swiss-Prot: Q9NQ36.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
内皮分泌蛋白厂颁鲍叠贰2抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 **学 神经生物学 干细胞 血管内皮细胞 内皮细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid