尾型同源盒转录因子4抗体
规格:1尘驳/1尘濒
英文名: CDX4
别名: Caudal-type homeobox protein 4; CDX4; CDX4_HUMAN; Homeobox protein CDX-4.
分子量: 30kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from Human CDX4
交叉反应:Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞核
尾型同源盒转录因子4抗体产物介绍:background: Cdx1, Cdx2 and Cdx4 are members of the caudal-type homeobox family of genes, which are homologs of the Drosophila “caudal” gene required for anterior-posterior regional identity. The proteins encoded by these genes are transcription factors which play an important role in development by regulating the expression of Hox genes. Hox genes play a 尾型同源盒转录因子4抗体fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. Cdx4 is a major positive regulator of the expression of all Hox family members. Due to its critical role as a regulator, Cdx4 is a direct target of the canonical Wnt pathway. The loss of Cdx4 can result in the development of an expanded hindbrain, while the尾型同源盒转录因子4抗体 overexpression of Cdx4 may cause the hindbrain to lose its distinct segmental features and resemble the spinal cord. Subcellular Location: Nucleus. Similarity: Belongs to the Caudal homeobox family. Contains 1 homeobox DNA-binding domain. Database links: UniProtKB/Swiss-Prot: O14627.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
尾型同源盒转录因子4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 干细胞 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid