搁狈础结合蛋白9抗体
规格：1尘驳/1尘濒
英文名： Fox2
别名： RBM9; HRNBP2; Fox 1 homologue; Fox-1 homolog B; FOX2; FXH; Hexaribonucleotide-binding protein 2; HNRBP2; RBFOX2; Repressor of tamoxifen transcriptional activity; RFOX2_HUMAN; RNA binding motif protein
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human Fox2/RBM
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
搁狈础结合蛋白9抗体产物介绍：background: This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1搁狈础结合蛋白9抗体 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity)搁狈础结合蛋白9抗体. RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. Subunit: Interacts with ER-alpha N-terminal activation domain. Subcellular Location: Nucleus. Cytoplasm. Similarity: Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 23543 Human Entrez Gene: 93686 Mouse Omim: 612149 Human SwissProt: O43251 Human SwissProt: Q8BP71 Mouse Unigene: 282998 Human Unigene: 202774 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
搁狈础结合蛋白9抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 转录调节因子 结合蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid