色氨酸羟化酶抗体
规格：1尘驳/1尘濒
英文名： TPH
别名： MGC119994; TPH 1; TPH; TPH1; TPRH; Tryptophan 5 hydroxylase 1; Tryptophan 5 monooxygenase 1; Tryptophan 5 monooxygenase; Tryptophan hydroxylase 1; Tryptophan 5-hydroxylase 1; TPH1_HUMAN.
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TPH
交叉反应：Human, Mouse, Rat, Chicken, Dog, Horse, Rabbit,
细胞定位：
色氨酸羟化酶抗体产物介绍：background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]. Subunit: Homotetramer. Tissue Specificity:色氨酸羟化酶抗体 Isoform 2 seems to be less widely expressed than isoform 1. Similarity: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. Contains 1 ACT domain. Gene ID: 121278 Database links: Entrez Gene: 121278 Human Entrez Gene: 216343 Mouse Entrez Gene: 100009100 Rabbit Entrez Gene: 317675 Rat Omim: 607478 Human SwissProt: Q8IWU9 Human SwissProt: Q8CGV2 Mouse SwissProt: 色氨酸羟化酶抗体Q8CGU9 Rat Unigene: 376337 Human Unigene: 736576 Human Unigene: 31597 Mouse Unigene: 28510 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 色氨酸在脑中首先由色氨酸羟化酶(tryoptophan hydroxylase)催化生成5羟色氨酸(5hydroxytryptophan)，再经脱羧酶作用生成5羟色胺，色氨酸羟化酶（TPH）是5-HT生物合成的限速酶，因此，色氨酸羟化酶的缺少可导致5-羟色胺的含量下降。色氨酸羟化酶主要在肝脏内代谢。
色氨酸羟化酶抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid