细胞周期蛋白厂骋2狈抗体
规格:1尘驳/1尘濒
英文名: Striatin 3
别名: Striatin3; Striatin-3; Striatin 3; Cell cycle autoantigen SG2NA; Cell cycle S/G2 nuclear autoantigen; GS2NA; nuclear autoantigen; S/G2 antigen; SG2NA; Striatin 3; Striatin, calmodulin binding protein
分子量: 87kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Striatin
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位:细胞浆 细胞膜
细胞周期蛋白厂骋2狈抗体产物介绍:background: Striatin, SG2NA, and zinedin, the three mammalian members of the striatin family, are multimodular, WD repeat and calmodulin-binding proteins. Zinedin and SG2NA share with striatin identical protein-protein interaction domains and the same overall domain structure. All three proteins are both cytosolic and membrane-bound and bind calmodulin in the presence of calcium. Striatin is a neuronal, intracellular protein strictly expressed in the somato-dendritic compartment, including spines and subsets of neurons, and is细胞周期蛋白厂骋2狈抗体 considered as a marker of neuronal polarity. Downregulation of striatin, which is expressed in a few subsets of neurons, impairs the growth of dendrites as well as rat locomotor activity. Zinedin is mainly expressed in the central nervous system, whereas SG2NA is mainly expressed in the brain and muscle. Function: Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.细胞周期蛋白厂骋2狈抗体 Subunit: Interacts with protein phosphatase 2A (PP2A) (Potential). Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Similarity: Belongs to the WD repeat striatin family. Contains 6 WD repeats. Gene ID: 29966 Database links: Entrez Gene: 29966 Human Entrez Gene: 94186 Mouse Entrez Gene: 114520 Rat SwissProt: Q13033 Human SwissProt: Q9ERG2 Mouse SwissProt: P58405 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞周期蛋白厂骋2狈抗体产物应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导 细胞周期蛋白 细胞膜受体 结合蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid