小肠钠通道蛋白5抗体
规格：1尘驳/1尘濒
英文名： ACCN5
别名： amiloride sensitive cation channel 5, intestinal; Amiloride sensitive sodium channel;intestine Na+ channel; amiloride-sensitive cation channel 5; HINAC; INAC; ASIC5_HUMAN.
分子量： 57kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ACCN5
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：细胞膜
小肠钠通道蛋白5抗体产物介绍：background: ACCN5 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or 小肠钠通道蛋白5抗体heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride. Function: ACCN5 belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. Subunit: Homotrimer or heterotrimer with other ASIC proteins. Subcellular Location:小肠钠通道蛋白5抗体 Cell membrane; Multi-pass membrane protein. Tissue Specificity: Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum. Similarity: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC5 subfamily. Gene ID: 51802 Database links: Entrez Gene: 51802 Human SwissProt: Q9NY37 Human Unigene: 381349 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
小肠钠通道蛋白5抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 通道蛋白 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid