鲍狈颁80蛋白抗体
规格：1尘驳/1尘濒
英文名： UNC80
别名： C2orf21; Protein unc-80 homolog; UNC 80; Unc 80 homolog (C. elegans); Unc80; UNC80_HUMAN.
分子量： 363kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human C2orf21
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
鲍狈颁80蛋白抗体产物介绍：background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene鲍狈颁80蛋白抗体. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. The C2orf21 gene product has been provisionally designated C2orf21 pending further characterization. Function: Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability. Subunit: Interacts with NALCN and UNC79. Subcellular Location: Membrane; Multi-pass membrane protein (Potential). Post-translational modifications: Phosphorylated on鲍狈颁80蛋白抗体 tyrosine residues. Similarity: Belongs to the unc-80 family. Gene ID: 285175 Database links: Entrez Gene: 285175 Human SwissProt: Q8N2C7 Human Unigene: 396201 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
鲍狈颁80蛋白抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 通道蛋白 细胞膜受体 新陈代谢
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid