嗜铬粒蛋白颁抗体
规格：1尘驳/1尘濒
英文名： Chromogranin C
别名： CHGC; Chromogranin-C; MEN1; SCG2; SCG2_HUMAN; Secretogranin II; Secretogranin-2; Secretoneurin; Secretoneurin included; SgII; SN.
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Chromogr
交叉反应：Human, Mouse, Rat, Dog, Horse,
细胞定位：分泌型蛋白
嗜铬粒蛋白颁抗体产物介绍：background: Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine, neuroendocrine and neuronal tissue. Family members include chromogranin A (Chr-A); chromogranin B (Chr-B), also known as secretogranin I; chromogranin C (also known as secretogranin II or Sg II); and secretogranin III (Sg III or SCG3). High levels of Chr-A expression are characteristic of neuroendocrine tumors. Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, exocrine pancreatic secretion and gastric acid secretion. Pancreastatin exists as two forms; the major form is expressed in stomach and colon extracts. In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, while levels of Chr-A and Chr-B showed little or no increase. 嗜铬粒蛋白颁抗体Sg III is an acidic secretory protein expressed in neuronal and endocrine cells. In the anterior lobe of the rat pituitary gland, Sg III is present in mammotropes and thyrotropes, moderately in gonadotropes and corticotropes, though not in somatotropes. Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes. Function: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides. Subcellular Location: Secreted. Neuroendocrine and endocrine secretory 嗜铬粒蛋白颁抗体granules. Tissue Specificity: Belongs to the chromogranin/secretogranin protein family. Similarity: Belongs to the chromogranin/secretogranin protein family. Gene ID: 7857 Database links: Entrez Gene: 7857 Human Entrez Gene: 20254 Mouse Entrez Gene: 24765 Rat Omim: 118930 Human SwissProt: P13521 Human SwissProt: Q03517 Mouse SwissProt: P10362 Rat Unigene: 516726 Human Unigene: 5038 Mouse Unigene: 45602 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
嗜铬粒蛋白颁抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid