叁磷酸腺苷受体笔2齿6抗体
规格:1尘驳/1尘濒
英文名: P2RX6
别名: ATP receptor; P2RX6; P2RX6_HUMAN; P2RXL1; P2X purinoceptor 6; P2X6; P2XM; Purinergic receptor; Purinergic receptor P2X like 1; Purinergic receptor P2X-like 1; Skeletal muscle expressed P2X.
分子量: 49kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human P2RX6
交叉反应:Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位:细胞膜
叁磷酸腺苷受体笔2齿6抗体产物介绍:background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. 叁磷酸腺苷受体笔2齿6抗体The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. Function: Receptor for ATP that acts as a ligand-gated ion channel. Subunit: Functional P2XRs are organized as homomeric and heteromeric trimers Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed predominantly in skeletal muscle. Similarity: Belongs to the P2X receptor family. Gene ID: 9127 Database links: Entrez Gene: 9127 Human Entrez Gene: 18440 Mouse Entrez Gene:叁磷酸腺苷受体笔2齿6抗体 25041 Rat Omim: 608077 Human SwissProt: O15547 Human SwissProt: O54803 Mouse SwissProt: P51579 Rat Unigene: 113275 Human Unigene: 8032 Mouse Unigene: 10258 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
叁磷酸腺苷受体笔2齿6抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 神经生物学 信号转导 细胞凋亡 通道蛋白 细胞膜受体 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid