谷氨酸受体δ1/骋濒耻搁-δ1抗体
规格：1尘驳/1尘濒
英文名： GRID1
别名： GluR delta 1; GluR delta 1 subunit; GluR delta-1 subunit; Glutamate receptor delta 1 subunit; Glutamate receptor delta-1 subunit; Glutamate receptor ionotropic delta 1; GRID 1; Grid1; GRID1_HUMAN; KIA
分子量： 110kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GRID1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
细胞定位：细胞膜
谷氨酸受体δ1/骋濒耻搁-δ1抗体产物介绍：background: Glutamate receptors mediate most excitatory neurotransmissions in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are divided into two categories, namely NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors consist of seven structurally related subunits, designated GluR-1 to -7, and are primarily responsible for fast excitatory谷氨酸受体δ1/骋濒耻搁-δ1抗体 neurotransmissions carried out by glutamate. GluR-delta 1 (Glutamate receptor delta-1 subunit), also known as GRID1, is a multi-pass membrane protein that belongs to the kainate/AMPA receptor family and is expressed primarily in the brain. Localized to the cell junction and the postsynaptic cell membrane, GluR-delta 1 functions as a glutamate receptor that regulates synaptic transmissions in the central nervous system (CNS) and is thought to play an important role in synaptic plasticity. Defects in the gene encoding GluR-delta 1 are associated with schizophrenia, a chronic and severe brain disorder. Function: Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in 谷氨酸受体δ1/骋濒耻搁-δ1抗体the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Subcellular Location: Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein (By similarity). Similarity: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID1 subfamily. Gene ID: 2894 Database links: Entrez Gene: 2894 Human Entrez Gene: 14803 Mouse GenBank: NP_060021.1 Human Omim: 610659 Human SwissProt: Q9ULK0 Human SwissProt: Q61627 Mouse Unigene: 530653 Human Unigene: 121569 Mouse Unigene: 413604 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷氨酸受体δ1/骋濒耻搁-δ1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 通道蛋白 细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid