G氨基丁酸受体γ3/GABAA Rγ3抗体
规格:1尘驳/1尘濒
英文名: GABRG3
别名: GABA A Receptor gamma 3; GABA(A) receptor; GABA(A) receptor subunit gamma 3; GABR G3; GABRG 3; GABRG3; Gamma aminobutyric acid (GABA) A receptor gamma 3; Gamma aminobutyric acid A receptor gamma 3; Ga
分子量: 52kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GABRG3/G
交叉反应:Human, Mouse, Rat,
细胞定位:细胞膜
G氨基丁酸受体γ3/GABAA Rγ3抗体产物介绍:background: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this geneG氨基丁酸受体γ3/GABAA Rγ3抗体 is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012] Function: GABA A Receptor gamma 3, is the ligand-gated ion channel that GABA A (gamma aminobutyric acid) exerts its inhibitory neurotransmitter funtion through. Subunit: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Subcellular Location: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Post-translational modifications: May be palmitoylated Similarity: Belongs to the ligand-gated ion G氨基丁酸受体γ3/GABAA Rγ3抗体channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG3 sub-subfamily. Gene ID: 2567 Database links: Entrez Gene: 2567 Human Entrez Gene: 14407 Mouse Entrez Gene: 79211 Rat Omim: 600233 Human SwissProt: Q99928 Human SwissProt: P27681 Mouse SwissProt: P28473 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G氨基丁酸受体γ3/GABAA Rγ3抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:神经生物学 通道蛋白 细胞膜受体 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid