葡萄糖转运蛋白3抗体
规格：1尘驳/1尘濒
英文名： GLUT3
别名： brain; facilitated glucose transporter member 3; Glucose Transporter GLUT3 ; FLJ90380; Glucose Transporter Type 3; Glucose transporter type 3 brain; GLUT 3; GLUT-3; GLUT3; GTR3_HUMAN; SLC2A3; Solute C
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GLUT3
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig,
细胞定位：细胞膜
葡萄糖转运蛋白3抗体产物介绍：background: may act as a glucose transporter in neurons; may mediate increasd glucose uptake in response to neuronal injury. Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF1 induced signaling. GLUT3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT3 staining is also detectable in human cancers including those of the ovary, lung, and testis. Alternative names: FLJ90380; Glucose Transporter Type 3; Glucose transporter type 3 brain; GLUT 3; GLUT3; SLC2A3; Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 3. Function: Facilitative glucose transporter. Probably a葡萄糖转运蛋白3抗体 neuronal glucose transporter. Subcellular Location: Cell membrane; Multi-pass membrane protein. Melanosome. Tissue Specificity: Highly expressed in brain. Expressed in many tissues. Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. Gene ID: 6515 Database links: Entrez Gene: 6515 Human Entrez Gene: 20527 Mouse Entrez Gene: 25551 Rat Omim: 葡萄糖转运蛋白3抗体138170 Human SwissProt: P11169 Human SwissProt: P32037 Mouse SwissProt: Q07647 Rat Unigene: 419240 Human Unigene: 395108 Mouse Unigene: 95055 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 交换和转运（Trafficking and Transport） GLUT-3属于溶质运载蛋白家族成员（solute carrier family），主要功能是转载葡萄糖进入上皮细胞。 目前主要用于糖尿病肾病和视网膜病变的研究，也是肾小球系膜细胞上的主要葡萄糖转运体。GLUT3的功能状态直接影响系膜细胞的糖代谢及功能变化。 近期，研究人员也用来区别一些良、恶性肿瘤的鉴别。
葡萄糖转运蛋白3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:50-300 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid