周期素驰/齿抗体
规格：1尘驳/1尘濒
英文名： Cyclin Y
别名： C10orf9; CBCP1; CCNX; CCNY; CFP1; Chromosome 10 open reading frame 9; Cyclin box carrying protein 1; Cyclin box protein 1; Cyclin fold protein 1; Cyclin X; Cyclin Y; CCNY_HUMAN.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Cyclin Y
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞核 细胞浆 细胞膜
周期素驰/齿抗体产物介绍：background: Cyclin Y is a 341 amino acid protein belonging to the cyclin family. Cyclin Y exists as three alternatively spliced isoforms and contains a cyclin N-terminal domain. Cyclin Y may control cell division cycles and regulate cyclin-dependent kinases. Cell proliferation is controlled at specific stages of the cell cycle by distinct protein kinase complexes. These complexes consist of a catalytic subunit associating with a specific regulatory subunit to form the active kinase. The cyclins, which include cyclin A, B, C, D, E, F, G, H, I, K, L, T, Y and their related proteins, including Dbf4, comprise the regulatory subunits of these kinase complexes. The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit. Unlike the catalytic subunit, which is expressed周期素驰/齿抗体 continually, the expression and stability of the regulatory subunit fluctuates depending on the stage of the cell cycle, thereby regulating kinase activity. Function: Cyclin Y is a cyclin which plays a role in the control of cell division cycles and regulation of cyclin dependent kinases (e.g., CDC2; MIM 116940). Single nucleotide polymorphism in Cyclin Y gene is associated with Crohn's disease and ulcerative colitis. Subunit: Interacts with CDK14, CDK16 and LRP6. Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side. Isoform 3: Nucleus Tissue Specificity: Widely 周期素驰/齿抗体expressed. Post-translational modifications: Ubiquitinated; leading to its degradation. Similarity: Belongs to the cyclin family. Cyclin Y subfamily. Contains 1 cyclin N-terminal domain. Database links: Entrez Gene: 219771 Human Entrez Gene: 67974 Mouse Omim: 612786 Human SwissProt: Q8ND76 Human SwissProt: Q8BGU5 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
周期素驰/齿抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 细胞周期蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid