5-羟色胺受体2叠抗体
规格：1尘驳/1尘濒
英文名： 5HT2B Receptor
别名： SR-2B; 5 HT 2B; 5 HT 2B receptor; 5 HT(2B); 5 HT2B; 5 hydroxytryptamine (serotonin) receptor 2B; 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled; 5 hydroxytryptamine 2B receptor; 5 hydro
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human 5HT2B Re
交叉反应：贬耻尘补苍,
细胞定位：细胞膜
5-羟色胺受体2叠抗体产物介绍：background: Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. The SR-2 receptors are comprised of three subtypes, SR-2A, SR-2B and SR-2C, which activate phospholipase C and release intracellular stores of calcium in response to serotonin. SR-2A has a specific role5-羟色胺受体2叠抗体 in tracheal smooth muscle contraction, bronchoconstriction and mediating aldosterone production, and it is also thought to play a role in several psychiatric disorders, including depression and schizophrenia. SR-2B is expressed in embryonic and cardiovascular tissues, gut and brain and plays an important role in the pathology of cardiac disorders. SR-2C is thought to mediate the effects of atypical antipsychotic drugs. Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger 5-羟色胺受体2叠抗体system. Plays a role in the regulation of impulsive behavior. Subunit: Interacts with MPDZ. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 3357 Database links: Entrez Gene: 3357 Human Omim: 601122 Human SwissProt: P41595 Human Unigene: 421649 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
5-羟色胺受体2叠抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 细胞膜受体 G蛋白偶联受体 新陈代谢 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid