α2颁-础搁肾上腺素能受体抗体
规格：1尘驳/1尘濒
英文名： ADRA2C
别名： alpha 2C Adrenergic Receptor; Adra 2c; Adra 2c; ADRA2C; ADRA2L2; ADRA2L2; ADRA2RL2; ADRA2RL2; ADRARL2; ADRARL2; Adrenergic alpha 2C receptor; Adrenoceptor alpha 2C; Alpha 2C adrenergic receptor; Alpha
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ADRA2C/a
交叉反应：Human, Mouse, Rat, Dog, Pig,
细胞定位：细胞膜
α2颁-础搁肾上腺素能受体抗体产物介绍：background: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2Cα2颁-础搁肾上腺素能受体抗体 subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008] Function: The alpha 2C Adrenergic Receptor controls the release of neurotransmitter from central adrenergic neurons and from sympathetic nerves in the heart. This receptor also plays a role in cognitive and behavioral function. Two variants are produced by alternative splicing. Alpha 2C Adrenergic Receptor has been reported extensively in the brain. Blood, corpus cavermosum, kidney, and heart tissues have also been reported to express the protein. Subcellular Location: Cell membrane; Multi-passα2颁-础搁肾上腺素能受体抗体 membrane protein. Similarity: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2C sub-subfamily. Gene ID: 152 Database links: Entrez Gene: 152 Human Entrez Gene: 11553 Mouse Entrez Gene: 24175 Rat Omim: 104250 Human SwissProt: P18825 Human SwissProt: Q01337 Mouse SwissProt: P22086 Rat Unigene: 123022 Human Unigene: 57205 Mouse Unigene: 10297 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
α2颁-础搁肾上腺素能受体抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 生长因子和** 细胞膜受体 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid