膜蛋白相互作用蛋白搁骋厂16抗体
规格：1尘驳/1尘濒
英文名： MIR16
别名： EC 3.1.4.44; GDE1; Glycerophosphodiester phosphodiesterase 1; Membrane interacting protein of RGS16; RGS16 interacting membrane protein; GDE1_HUMAN.
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MIR16/GD
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：细胞浆 细胞膜
膜蛋白相互作用蛋白搁骋厂16抗体产物介绍：background: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. 膜蛋白相互作用蛋白搁骋厂16抗体The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: MIR6 has glycerophosphoinositol phosphodiesterase activity. Subunit: Interacts with RGS16 (By similarity). Interacts with PRAF2. Subcellular Location: Cytoplasmic. Membrane; Multi-pass membrane protein (By similarity). 膜蛋白相互作用蛋白搁骋厂16抗体Tissue Specificity: Widely expressed. Post-translational modifications: N-glycosylated Similarity: Belongs to the glycerophosphoryl diester phosphodiesterase family. Contains 1 GDPD domain. Database links: Entrez Gene: 51573 Human Omim: 605943 Human SwissProt: Q9NZC3 Human Unigene: 512607 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜蛋白相互作用蛋白搁骋厂16抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid