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氯离子通道蛋白6抗体

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产物名称: 氯离子通道蛋白6抗体
产物型号: CLIC6
产物展商: 单克隆抗体/多克隆抗体
产物文档: 无相关文档

简单介绍

氯离子通道蛋白6抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。氯离子通道蛋白6抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


氯离子通道蛋白6抗体  的详细介绍

氯离子通道蛋白6抗体

规格:1尘驳/1尘濒

英文名: CLIC6

别名: Chloride channel form A; Chloride intracellular channel 6; Chloride intracellular channel protein 6; CLIC1L; Clic6; CLIC6_HUMAN; Parchorin.

分子量: 73kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human CLIC6

交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,

细胞定位:细胞浆 细胞膜

氯离子通道蛋白6抗体产物介绍:background: CLIC6 (chloride intracellular channel 6) is believed to play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. The CLIC6 gene is a rare example of large-scale segmental paralogy in which a large (approximately 500 kb) segment on human chromosome (HC) 21 (21q22) is triplicated on HC 1 and HC 6. CLIC6 is also known to interact with dopamine receptors DRD2, DRD3 and DRD4. CLIC6 is primarily expressed in the cytoplasm, however, upon chloride ion efflux from the cell,氯离子通道蛋白6抗体 CLIC6 is translocated to the plasma membrane. CLIC6 has been identified in brain, placenta, pancreas and liver. Function: May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport. Subunit: Interacts with dopamine receptors DRD2, DRD3 and DRD4 Subcellular Location: Cytoplasm. Cell membrane. Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane. Tissue Specificity: Expressed in brain, placenta, 氯离子通道蛋白6抗体pancreas and liver. Post-translational modifications: Phosphorylated. Similarity: Belongs to the chloride channel CLIC family. Contains 1 GST C-terminal domain. Database links: UniProtKB/Swiss-Prot: Q96NY7.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

氯离子通道蛋白6抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:肿瘤  神经生物学  通道蛋白  细胞膜受体  G蛋白偶联受体  新陈代谢  G蛋白信号  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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