骋蛋白偶联受体119抗体
规格:1尘驳/1尘濒
英文名: GPR119
别名: G protein coupled receptor 119; G protein coupled receptor 2; G-protein coupled receptor 119; Glucose dependent insulinotropic receptor; Glucose-dependent insulinotropic receptor; GP119_HUMAN; GPCR 2;
分子量: 37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GPCR GPR
交叉反应:Human, Mouse, Rat, Pig, Horse, Rabbit,
细胞定位:细胞膜
骋蛋白偶联受体119抗体产物介绍:background: This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the 骋蛋白偶联受体119抗体treatment of type 2 diabetes.[provided by RefSeq, Jan 2010]. Function: Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway. Subcellular Location: 骋蛋白偶联受体119抗体Cell membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in the pancreas, especially in the islets. Similarity: Belongs to the G-protein coupled receptor 1 family. Database links: UniProtKB/Swiss-Prot: Q8TDV5.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
骋蛋白偶联受体119抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞膜受体 糖尿病 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid