促代谢型谷氨酸受体2+3抗体
规格：1尘驳/1尘濒
英文名： MGLUR2 + MGLUR3
别名： Metabotropic Glutamate Receptor 2+3; G protein coupled receptor family C group 1 member B; G protein coupled receptor family C group 1 member C; GLUR2; GLUR3; Glutamate receptor homolog; Glutamate rec
分子量： 95kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human mGLUR2 +
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞膜
促代谢型谷氨酸受体2+3抗体产物介绍：background: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic 促代谢型谷氨酸受体2+3抗体properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. The activity of GRM2 and GRM3 receptors are mediated by a G-protein that inhibits adenylate cyclase activity. Function: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. Subunit: Interacts促代谢型谷氨酸受体2+3抗体 with GRASP Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Widely expressed in different regions of the brain as well as in fetal brain. Similarity: Belongs to the G-protein coupled receptor 3 family. Database links: UniProtKB/Swiss-Prot: Q14416.2 UniProtKB/Swiss-Prot: Q14832.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
促代谢型谷氨酸受体2+3抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 新陈代谢 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid