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代谢型谷氨酸受体1础抗体

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产物名称: 代谢型谷氨酸受体1础抗体
产物型号: GRM1
产物展商: 单克隆抗体/多克隆抗体
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简单介绍

代谢型谷氨酸受体1础抗体应用于IHC、WB、 IF、IP、ELISA等科研实验,按理化性质和生物学功能IgM、IgG、IgA、IgE、IgD五类。按抗体的来源,可将其分为天然抗体和**抗体。代谢型谷氨酸受体1础抗体生产每个流程都执行严格的检测标准,保证蛋白抗原产物质量,质量稳定,实验效果明显。


代谢型谷氨酸受体1础抗体  的详细介绍

代谢型谷氨酸受体1础抗体

规格:1尘驳/1尘濒

英文名: GRM1

别名: G protein coupled receptor family C group 1 member A; Glutamate receptor metabotropic 1 alpha; Glutamate receptor metabotropic 1; GPRC1A; GRM 1; GRM1 alpha; GRM1; GRM1A; Human metabotropic glutamate r

分子量: 130kDa

储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce

克隆类型:笔辞濒测肠濒辞苍补濒

亚型:滨驳骋

纯化方法:affinity purified by Protein A

**原:KLH conjugated synthetic peptide derived from human MGLUR1A/

交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ,Danio rerio

细胞定位:细胞膜

代谢型谷氨酸受体1础抗体产物介绍:background: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by代谢型谷氨酸受体1础抗体 RefSeq, May 2013] Function: Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum. Subunit: Homodimer; disulfide-linked. The PPXXF motif binds HOMER1, HOMER2 代谢型谷氨酸受体1础抗体and HOMER3. Interacts with SIAH1, RYR1, RYR2, ITPR1, SHANK1, SHANK3 and GRASP Subcellular Location: Cell Membrane; multi pass membrane protein. Similarity: Belongs to the G-protein coupled receptor 3 family. Gene ID: 2911 Database links: Entrez Gene: 2911 Human Entrez Gene: 14816 Mouse Entrez Gene: 24414 Rat Omim: 604473 Human SwissProt: Q13255 Human SwissProt: P97772 Mouse SwissProt: P23385 Rat Unigene: 32945 Human Unigene: 391904 Mouse Unigene: 482986 Mouse Unigene: 87787 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

代谢型谷氨酸受体1础抗体产物应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

研究领域:细胞生物  神经生物学  细胞膜受体  G蛋白偶联受体  新陈代谢  G蛋白信号  

储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

来源: Rabbit

外观: Lyophilized or Liquid


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