少突细胞髓磷脂糖蛋白抗体
规格：1尘驳/1尘濒
英文名： Omgp
别名： olyigodendrocyte myelin glycoprotein; OMG; OMGP; Oligodendrocyte-myelin glycoprotein; OMGP_HUMAN.
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Omgp
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：
少突细胞髓磷脂糖蛋白抗体产物介绍：background: Oligodendrocyte myelin glycoprotein (OMG) is a glycosylphosphatidylinositol (GPI)-anchored CNS myelin protein, which is a potent inhibitor of neurite outgrowth in cultured neurons, and contributes significantly to the inhibitory activity associated with CNS myelin. Function: Cell adhesion molecule contributing to the interactive process required for myelination in 少突细胞髓磷脂糖蛋白抗体the central nervous system. Subunit: Binds to RTN4R. Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Tissue Specificity: Oligodendrocytes and myelin of the central nervous system. Post-translational modifications: O-glycosylated in its Ser/Thr-rich repeat domain (Potential). Similarity: Contains 8 LRR (leucine-rich) repeats. Contains 1 LRRNT domain. Gene ID: 4974 Database links: Entrez Gene: 407186少突细胞髓磷脂糖蛋白抗体 Cow Entrez Gene: 4974 Human Entrez Gene: 100172122 Orangutan Omim: 164345 Human SwissProt: P23515 Human Unigene: 113874 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. OMgp也是髓鞘糖蛋白的一种，在发育期促进轴突生长,成熟期抑制轴突生长.其抑制作用主要由髓鞘来源的抑制分子的共同受体NgR介导,在神经营养因子受体p75NTR以及小GTP酶Rho等信号分子的共同参与下完成.
少突细胞髓磷脂糖蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 信号转导 细胞凋亡
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid