配对盒基因1抗体
规格：1尘驳/1尘濒
英文名： PAX1
别名： HUP48; OTTHUMP00000030407; Paired box 1; Paired box gene 1; Paired box protein Pax 1; Paired domain gene HuP48; PAX 1; PAX1_HUMAN.
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PAX1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
配对盒基因1抗体产物介绍：background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with 配对盒基因1抗体vertebral malformations. [provided by RefSeq, Mar 2012] Function: This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column. 配对盒基因1抗体Subcellular Location: Nucleus. Similarity: Contains 1 paired domain. Gene ID: 5075 Database links: Entrez Gene: 5075 Human Entrez Gene: 18503 Mouse Entrez Gene: 311505 Rat Omim: 167411 Human SwissProt: P15863 Human SwissProt: P09084 Mouse Unigene: 349082 Human Unigene: 315502 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 同源结构域蛋白（Homeodomain Proteins） PAX蛋白在器官发生中起关键作用，包括促进细胞增殖、细胞世系的特异化、迁移和存活。一些PAX基因在多种癌症类型中表达，因此可以作为有用的肿瘤标志物。
配对盒基因1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 发育生物学 信号转导 干细胞 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid