双甲基精氨酸水解酶1抗体
规格:1尘驳/1尘濒
英文名: DDAH1
别名: DDAH; DDAH I; DDAH-1; DDAH1; DDAH1_HUMAN; DDAHI; Dimethylargininase 1; Dimethylargininase-1; Dimethylarginine dimethylaminohydrolase 1; N(G); N(G)-dimethylarginine dimethylaminohydrolase 1; NG NG dime
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human DDAH1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位:
双甲基精氨酸水解酶1抗体产物介绍:background: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, 双甲基精氨酸水解酶1抗体the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1). Function: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.双甲基精氨酸水解酶1抗体 Subunit: Monomer. Tissue Specificity: Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. Similarity: Belongs to the DDAH family. Database links: UniProtKB/Swiss-Prot: O94760.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet 双甲基精氨酸水解酶1抗体tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 神经生物学 血管内皮细胞
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid