转录因子21抗体
规格：1尘驳/1尘濒
英文名： SOX21
别名： SOX21_HUMAN; Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is respo
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SOX21
交叉反应：Human, Mouse, Rat, Chicken, Cow,
细胞定位：细胞核
转录因子21抗体产物介绍：background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various 转录因子21抗体animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Function: SOX21 is a transcription factor whose presence is key for the generation of neurons from precursor cells. The decision of neural cells to remain as progenitors 转录因子21抗体or commit to neuronal differentiation seems to depend on the intrinsic balance of Sox21 and Sox1-3 activity Subcellular Location: Nuclear Similarity: Contains 1 HMG box DNA-binding domain. Database links: UniProtKB/Swiss-Prot: Q9Y651.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子21抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 神经生物学 转录调节因子 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid