神经丛蛋白础4抗体
规格:1尘驳/1尘濒
英文名: Plexin A4
别名: FAYV2820; KIAA1550; PLEXA4; Plexin-A4; PlexinA4; PLXA4_HUMAN; PLXNA4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003.
分子量: 210kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Plexin A
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep,
细胞定位:细胞膜
神经丛蛋白础4抗体产物介绍:background: Forms a receptor complex with neuropilin-1 and can propagate semaphorin-3A elicited inhibitory signals into cells and neurons. Function: Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation神经丛蛋白础4抗体of down-stream signaling events in the cytoplasm Subunit: Interacts with NRP1 and NRP2 Subcellular Location: Cell membrane; Single-pass type I membrane protein Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the plexin family. Contains 4 IPT/TIG domains. Contains 3 PSI domains. Contains 1 Sema domain. Gene ID: 91584 Database神经丛蛋白础4抗体 links: Entrez Gene: 91584 Human Entrez Gene: 243743 Mouse Entrez Gene: 312213 Rat Omim: 604280 Human SwissProt: Q9HCM2 Human SwissProt: Q80UG2 Mouse Unigene: 511454 Human Unigene: 444029 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经丛蛋白础4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:发育生物学 神经生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid