背板胶质乙酰酯酶抗体
规格：1尘驳/1尘濒
英文名： NOTUM
别名： NOTUM; notum pectinacetylesterase homolog (Drosophila); Notum pectinacetylesterase homolog; NOTUM_HUMAN.
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human NOTUM
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, 54kDa
细胞定位：分泌型蛋白
背板胶质乙酰酯酶抗体产物介绍：background: Notum is a 496 amino acid secreted protein that belongs to the pectinacetylesterase family and may deacetylate GlcNAc residues on cell surface glycans. The gene that encodes Notum consists of approximately 9,334 bases and maps to human chromosome 17q25.3. Encoding more than 1,200 genes, chromosome 17 comprises over 2.5% of the human genome. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for 背板胶质乙酰酯酶抗体maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of ovary, colon, prostate gland and fallopian背板胶质乙酰酯酶抗体 tubes. Function: May deacetylate GlcNAc residues on cell surface glycans. Subcellular Location: Secreted. Similarity: Belongs to the pectinacetylesterase family. Database links: UniProtKB/Swiss-Prot: Q6P988.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背板胶质乙酰酯酶抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid