胃泌素/蛙皮素抗体
规格：1尘驳/1尘濒
英文名： Gastrin
别名： Gastrin component II; Gastrin-34; Gastrin 34; Gastrin34; G34; Gastrin component III; Gastrin-17; Gastrin 17; Gastrin17; G17; GAS; GAST; Gastrin precursor; Bombesin; gastrin big; Gastrin-71; Gastrin 71
分子量： 2.1/3.9/6/8kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Gastrin
交叉反应：Human, Mouse, Rat, Pig, Rabbit,
细胞定位：分泌型蛋白
胃泌素/蛙皮素抗体产物介绍：background: Gastrin is mainly known by its first described role as a gastric acid-hormone but the protein also has the ability to promote cellular growth. More recently, gastrin has been suggested to induce leukocyte-endothelial cell interactions and to have a pro-inflammatory effect. Gastrin has two biologically active peptide forms, G34 and G17 and they activate two different receptors: the CCK-1 receptor, which has low affinity for gastrin but high affinity for the related hormone cholecystokinin (CCK), and the CCK-2 receptor, which has high affinity for both gastrin and CCK and mediates the acid-secretory as well as the proliferative effects of gastrin. Function: Gastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle胃泌素/蛙皮素抗体contraction and increases blood circulation and water secretion in the stomach and intestine. Subcellular Location: Secreted. Post-translational modifications: Two different processing pathways probably exist in antral G-cells. In the dominant pathway progastrin is cleaved at three sites resulting in two major bioactive gastrins, gastrin-34 and gastrin-17. In the putative alternative pathway, progastrin may be processed only胃泌素/蛙皮素抗体 at the most C-terminal dibasic site resulting in the synthesis of gastrin-71. Sulfation enhances proteolytic processing, and blocks peptide degradation. Levels of sulfation differ between proteolytically-cleaved gastrins. Thus, gastrin-6 is almost 73% sulfated, whereas the larger gastrins are less than 50% sulfated. Sulfation levels are also tissue-specific. Similarity: Belongs to the gastrin/cholecystokinin family. Gene ID: 2520 Database links: Entrez Gene: 2520 Human Entrez Gene: 14459 Mouse Omim: 137250 Human SwissProt: P01350 Human SwissProt: P48757 Mouse Unigene: 2681 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Gastrin又称蛙皮素（Bombesin），是一种含十七个氨基酸残基的多肽类**。它是由胃黏膜产生，可刺激胃液、盐酸、及消化酶的分泌。Gastrin还可刺激平滑肌收缩、增加血液循环和胃肠道液体的分泌。
胃泌素/蛙皮素抗体产物应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid