维甲酸诱导神经母细胞瘤蛋白1抗体
规格:1尘驳/1尘濒
英文名: NAV2
别名: HELAD1; Helicase, APC down regulated 1; KIAA1419; mCG 145366; mKIAA3015; NAV 2; Neuron navigator 2; POMFIL2; Pore membrane and/or filament interacting like protein 2; RAINB1; RAINB2; Retinoic acid ind
分子量: 268kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human NAV2/RAI
交叉反应:Human, Mouse, Dog, Cow, Horse, Rabbit,
细胞定位:细胞核
维甲酸诱导神经母细胞瘤蛋白1抗体产物介绍:background: This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Function: NAV2 protein shows high similarity to Caenorhabditis elegans, unc-53, that is required for axonal elongation of mechanosensory neurons, suggesting that these proteins are orthologs. Thus, NAV2 may be involved in the vitamin A metabolite, 维甲酸诱导神经母细胞瘤蛋白1抗体atRA (all-trans retinoic acid)-mediated neurite outgrowth. NAV2 possesses 3' to 5' helicase activity and exonuclease activity and is involved in the development of different sensory organs. Subcellular Location: Nuclear. Tissue Specificity: Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon 维甲酸诱导神经母细胞瘤蛋白1抗体cancers. Similarity: Belongs to the Nav/unc-53 family. Contains 1 CH (calponin-homology) domain. Database links: Entrez Gene: 89797 Human Omim: 607026 Human SwissProt: Q8IVL1 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
维甲酸诱导神经母细胞瘤蛋白1抗体产物应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 肿瘤细胞生物标志物
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid