颗粒细胞分化蛋白抗体
规格：1尘驳/1尘濒
英文名： Myotrophin
别名： FLJ31098; FLJ99857; GCDP; Granule cell differentiation protein; MTPN; MTPN_HUMAN; Myotrophin; Protein V 1; Protein V-1; V 1; MTPN_HUMAN.
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from humam Myotroph
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
细胞定位：细胞核 细胞浆
颗粒细胞分化蛋白抗体产物介绍：background: The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel 颗粒细胞分化蛋白抗体internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008] Function: Potential role in cerebellar morphogenesis. May function in differentiation of cerebellar neurons, particularly of granule cells. Seems to be associated with cardiac hypertrophy. Subunit: Interacts with RELA (By similarity). Interacts with the heterodimer formed by CAPZA1 and CAPZB. Subcellular Location: Cytoplasm (Probable). Nucleus (By similarity). Cytoplasm, perinuclear region (By similarity). Tissue Specificity: Ubiquitous. Similarity: Belongs to the myotrophin family. Contains 3 ANK repeats. Database颗粒细胞分化蛋白抗体 links: Entrez Gene: 136319 Human Entrez Gene: 14489 Mouse Entrez Gene: 79215 Rat Entrez Gene: 403487 Dog Omim: 606484 Human SwissProt: Q863Z4 Dog SwissProt: P58546 Human SwissProt: P62774 Mouse SwissProt: P62775 Rat SwissProt: Q7T2B9 Zebrafish Unigene: 602015 Human Unigene: 182746 Mouse Unigene: 3239 Rat Unigene: 75187 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
颗粒细胞分化蛋白抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 神经生物学 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid