神经细胞分化因子6抗体
规格：1尘驳/1尘濒
英文名： NEUROD6
别名： MATH2/NEUROD6; MATH2 / NEUROD6; Atoh 2; Atoh2; Atonal homolog 2; Atonal protein homolog 2; Atonal protein homolog2; bHLH a2 antibodybHLHa 2; bHLHa2; Class A basic helix-loop-helix protein 2; Helix loo
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human MATH2/NE
交叉反应：Human, Mouse, Rat, Cow, Monkey,
细胞定位：细胞核
神经细胞分化因子6抗体产物介绍：background: The Drosophila atonal gene produces a protein with basic helix loop helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system. Mammalian atonal homolog 2 (MATH-2) is a helix-loop-helix (HLH) transcription factor that is structurally homologous to the product of Drosophila atonal gene. MATH-2 is a 337 amino acid protein with an atonal-related basic HLH domain. In mice, expression of MATH-2 takes place by embryonic day 11.5 and initially localizes to the wall of brain 神经细胞分化因子6抗体vesicles and in the spinal cord. It is expressed in the cortical plate and the mantle layer in the developing central nervous system, and is limited to the nervous system in s. Adult mouse cerebrums produce a high level of MATH-2 RNA with lower levels in other neuronal tissues. Research studies suggest that MATH-2 may function as a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Function: Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the神经细胞分化因子6抗体 development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene. Subunit: Efficient DNA binding requires dimerization with another bHLH protein Subcellular Location: Nucleus. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. Database links: Entrez Gene: 63974 Human Entrez Gene: 11922 Mouse Entrez Gene: 500137 Rat Entrez Gene: 540464 Cow Omim: 611513 Human SwissProt: Q08DI0 Cow SwissProt: Q96NK8 Human SwissProt: P48986 Mouse Unigene: 45152 Human Unigene: 5106 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经细胞分化因子6抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞分化 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid