富含亮氨酸重复跨膜神经元蛋白4抗体
规格:1尘驳/1尘濒
英文名: LRRTM4
别名: Leucine rich repeat transmembrane neuronal 4; Leucine rich repeat transmembrane neuronal 4 protein; Leucine rich repeat transmembrane neuronal protein 4; Leucine-rich repeat transmembrane neuronal 4 p
分子量: 64kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:笔辞濒测肠濒辞苍补濒
亚型:滨驳骋
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human LRRTM4
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
富含亮氨酸重复跨膜神经元蛋白4抗体产物介绍:background: The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic ?/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The LRRTM protein family plays a role in the regulation of various cellular events during nervous system development. Localizing predominantly to the nervous system,富含亮氨酸重复跨膜神经元蛋白4抗体 LRRTM family members are known to exhibit synaptogenic activity. LRRTM4 (leucine-rich repeat transmembrane neuronal protein 4) is a 590 amino acid member of the LRRTM protein family. Expressed in neuronal tissues, LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system. A single-pass type I membrane protein, LRRTM4 contains 10 LRR repeats. 富含亮氨酸重复跨膜神经元蛋白4抗体LRRTM4 is expressed as two isoforms produced by alternative splicing. Function: May play a role in the development and maintenance of the vertebrate nervous system. Subcellular Location: Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein Tissue Specificity: Expressed in neuronal tissues. Similarity: Belongs to the LRRTM family. Contains 10 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. Contains 1 LRRNT domain. Database links: UniProtKB/Swiss-Prot: Q86VH4.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
富含亮氨酸重复跨膜神经元蛋白4抗体产物应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:10-200 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid