滨谤辞辩耻辞颈蝉同源蛋白1抗体
规格：1尘驳/1尘濒
英文名： IRX1
别名： Iroquois Homeobox Protein 1; Iroquois-class homeodomain protein IRX-1; IRXA1; IRX1_HUMAN.
分子量： 50kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：笔辞濒测肠濒辞苍补濒
亚型：滨驳骋
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human IRX1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
细胞定位：细胞核
滨谤辞辩耻辞颈蝉同源蛋白1抗体产物介绍：background: The Iroquois homeobox gene family of transcription factors regulate aspects of embryonic development including anterior/posterior and dorsal/ventral axis patterning in the central nervous system. The Iroquois family are clustered on two loci, IRXA and IRXB, which map to chromosomes 8 and 13 in mice. The IRXA group includes Irx1, Irx2 and Irx4; the IRXB group is comprises Irx3, Irx5 and Irx6. Irx1 and Irx2 are both widely expressed during development in the lung epithelium and also in the 滨谤辞辩耻辞颈蝉同源蛋白1抗体ventricular septum. Irx1 and Irx2 also play a role in digit formation (E11.5–E14.5). The Irx gene family members are each expressed in a distinct pattern during mouse heart development. Specifically, Irx1 and Irx2 are expressed in the ventricular septum and Irx3 is expressed in the ventricular trabeculated myocardium. In addition, Irx4 is expressed in the linear heart tube and the AV canal; Irx5 is expressed in the endocardium lining the ventricular and atrial myocardium. Furthermore, the IRX4 gene may modulate cardiac development and function. Although the heart of Irx4(-) mice appears to develop normally, Irx4(-) mice exhibit cardiomyopathy, including cardiac hypertrophy and decreased contractility. 滨谤辞辩耻辞颈蝉同源蛋白1抗体Function: IRX1 is a member of the Iroquois homeobox gene family. The genes from this family have multiple roles in vertebrate development. The gene encoding IRX1 is expressed in the brain, lung and gut during specific stages of mouse development. Subcellular Location: Nuclear Similarity: Belongs to the TALE/IRO homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 79192 Human Entrez Gene: 16371 Mouse Entrez Gene: 306659 Rat Omim: 606197 Human SwissProt: P78414 Human SwissProt: P81068 Mouse SwissProt: D4A9L1 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
滨谤辞辩耻辞颈蝉同源蛋白1抗体产物应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 细胞生物 发育生物学 神经生物学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid